September 14, 2022
September 14, 2022
SINGAPORE, September 14, 2022 - Lion TCR Pte Ltd, a clinical-stage biotech company specialized in the development and commercialisation of its proprietary engineered T Cell Receptor (TCR) products against infectious disease and its associated cancers, has been recognised as the ‘Most Promising Cell & Gene Therapy Startup in Asia’ category at the Asia-Pacific Cell & Gene Therapy Excellence Awards (ACGTEA) 2022, organised by IMAPAC. The award ceremony was held in conjunction with the 6th Cell & Gene Therapy World Asia 2022 conference on 14th – 15th of September at the Sheraton Tower in Singapore. Lion TCR managed to distinguish itself from other companies to win the recognition of the judges and industry leaders.
Conference Presentation and Award Ceremony
Lion TCR’s R&D Director Dr Wai Lu-En presented on ‘Advances in Liver Cancer Therapy Using our First-In-Class TCR-T Therapy’ as an invited speaker during the conference. Director of Technology and Manufacturing, Dr Sarene Koh, represented Lion TCR to receive the certificate and trophy for the ‘Most Promising Cell & Gene Therapy Startup in Asia’ award. Dr Wai Lu-En and Dr Sarene Koh are both A*STAR scholars, who obtained their PhDs from the prestigious Stanford University and Karolinska Institute respectively. They are the founding team members of the company, and joined Lion TCR’s scientific founder, Professor Antonio Bertoletti in the research and development of T-cell immunotherapy and the immuno-pathogenesis of hepatitis B virus infection. Dr Wai leads Lion TCR’s efforts to expand the TCR library and pipeline project, while Dr Koh leads Lion TCR's efforts on product development and process optimisation in T cell immuno-therapy.
Clinching the ‘Most Promising Cell & Gene Therapy Startup in Asia’ award represents the industry’s affirmation of the company’s achievements in immunotherapy. Lion TCR has obtained the world’s first Phase 1b/2 IND approval from the US FDA for its First-In-Class autologous TCR-T cell product (LioCyx-M004) for the treatment of HBV-related hepatocellular carcinoma (HCC). FDA has also granted Lion TCR the dual designations of Fast Track and Orphan Drug Designations (ODD) due to the novelty of LioCyx-M004 treatment and its efficacy in Phase I trials. Lion TCR’s endeavours to accelerate the pace of development and bring its products to patients faster.
About Lion TCR Pte Ltd
Lion TCR is a clinical-stage biotech company specialized in the development and commercialisation of its proprietary engineered T Cell Receptor (TCR) products against infectious disease and its associated cancers. As global leader in HBV-specific TCR redirected T cell therapy against HCC, the company is a biotech spin-off from Singapore’s Agency for Science, Technology and Research (A*STAR) and has global exclusive licenses of the technologies from A*STAR. Lion TCR has developed various TCR technology platforms including the TCR discovery as well as the autologous and allogeneic TCR that incorporate gene editing.
Asia-Pacific Cell & Gene Therapy Excellence Awards 2022 seeks to give recognition to exceptional cell & gene therapy pioneers, researchers, innovators and manufacturers that facilitate fast advancement in new therapies, R&D and manufacturing. Featuring top cell and gene therapy leaders in the industry, along with the new cell and gene therapy research development, latest advances and technologies and best practices in cell and gene manufacturing, the award applauds extraordinary leaders and trend-setters of today and inspires innovators of tomorrow.
IMAPAC is a prominent player in the biopharmaceutical community hosting networking sessions and conferences. It has organised many long running conferences such as the above Cell & Gene Therapy World Asia Conference as well as award ceremonies such as ACGTEA and the Asia-Pacific Bioprocessing Excellence Awards (ABEA) where notable winners include Cytiva and WuXi Biologics, where the latter was the winner for Bioprocessing Excellence in Viral Clearance and Safety in 2021 and 2022.
Lion TCR Announces Poster Presentation of Phase 1 Study for Lead Product LioCyx-M at AASLD The Liver Meeting 2022
Lion TCR Receives FDA Fast Track Designation for its HBV-specific TCR T Cell Therapy for Hepatocellular Carcinoma
Scientific Founder & Chairman, Professor Antonio Bertoletti Has Been Placed on Highly Cited Researchers 2021 List
Lion TCR Announces FDA Clearance of its IND Application for its Lead Investigational Product, LioCyx-M004, for Hepatocellular Carcinoma
Scientific Founder, Prof Antonio Bertoletti Appointed as Cellular Immunotherapy Infectious Diseases Lead for Singhealth Duke-NUS Cell Therapy Centre
Lion TCR Licenses and Duke-NUS Medical School ink an exclusive IP licensing agreement for Immunosuppressive Drug Resistant Anti-Cancer T-cells
Dr Wai Lu-En, Director of R&D, represented Lion TCR to share the latest developments to the Minister for Manpower and Second Minister for Trade and Industry Tan See Leng.
Scientific Founder, Prof Antonio Bertoletti Appointed in Cell and Gene Therapy Workgroup in Singapore
Lion TCR Announces Data Presentation for its lead T-cell product, LioCyx-M at EASL Digital Liver Cancer Summit 2021
HSA approval for clinical trial for Lion TCR’s lead product LioCyx-M to characterize changes in liver cancer tumor microenvironment
Lion TCR presents two abstracts of Phase 1 clinical trial data for lead product LioCyx-M at the 2020 Society for Immunotherapy of Cancer (SITC) Annual Meeting
Companion diagnostic assay for personalised immunotherapy for HBV-related liver cancer featured in A*STAR GIS website
Singapore’s first clinical trial approval for T cell engineered (TCR) immunotherapy for treatment of Liver cancer
Lion TCR receives US$ 20 million to fund its personalized T cell therapy clinical trials against Liver cancer
Scientific Founder, Prof. Antonio Bertoletti and Scientific Consultant, Dr Anthony Tanoto Tan of Lion TCR were awarded the SingHealth Duke-NUS Research Award 1st Prize 2018
US FDA grants Lion TCR two orphan drug designations of T cell therapy against Hepatocellular Carcinoma
Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient