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At Lion TCR

We hunt virus by harnessing the power of a patient’s own immune system to eliminate Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), with proven clinical safety and efficacy.

Our proprietary personalized TCR-T cell therapy has been applied in clinics for
• HBV related HCC
• Recurrent HCC post liver transplant 
• Chronic HBV infection


Largest patented TCR library in the world

Our library of HBV-specific TCR covers about 80% of the patient population with a broad range of HLA types, particularly those predominant in Asia where HBV is prevalent.

mRNA technology

Transient expression of our T-cells confers enhanced safety features which allows for conservation dose escalation design in clinical trials and future use for other cancer treatment.

State-of-the-art GMP production facility

A comprehensive facility for the manufacturing of our proprietary product for clinical use in compliance with Good-Manufacturing-Practice (GMP) guidelines.

Proven clinical safety and efficacy

A safer personalized treatment providing an approximately 3-fold increase in survival time compared to existing standard of care medication for liver cancer patients in our Phase 1 studies.


Our TCR-T cell therapy harnesses the patient’s own immune system to fight against viral infections and related cancers.


We are conducting ongoing clinical trials against hepatocellular carcinoma to evaluate the safety and efficacy of our TCR-T cells.

Investors & Media

Our proprietary TCR-T cell therapy platform is supported by robust research, in collaboration with renowned laboratories, in the areas of autologous & allogeneic T cells and gene editing technologies.

R&D Partners

Industry Partners

Hospital Partners

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